What is osteoporosis? developed and compiled ProjectAWARE Group 2001
derived from Latin, osteoporosis literally means porous bones that
includes both mineral (inorganic) and non-mineral (organic matrix)
components of bone. Osteoporosis is a progressive disease of bone in which bone tissue is usually
mineralized, but the bone is reduced and the structural integrity of
broken, it becomes increasingly fragile. becomes more porous and thinner. While the thin bone itself
not necessarily more prone to fracture, the bone that is both thin and fragile
more prone to fractures. 6, 34
Bone strength reflects the integration of two main features: bone density
and quality of bone tissue. Bone density expressed in grams per unit area of mineral
or volume, and in any individual is determined by peak bone mass
and the number of bone loss. Bone quality refers to architecture, turnover
accumulation of damage (eg microcracks) and mineralization. Osteoporosis
is an important risk factor for fractures, and the difference between risk
factors that affect bone metabolism and risk factors for fracture should be done
. Although the whole skeleton can be involved in postmenopausal osteoporosis,
bone loss is usually more in the spine, hip and ribs, and >> << status changes with progression of disease. Small, thin bone woman
there is another cause for concern than women with larger frames and heavier bones.
Race and ethnicity also appears to play a role. Women of Asian or European origin
more likely to develop osteoporosis, whereas women
African descent are less likely to be affected. Osteoporosis can be further characterized as primary or secondary. Primary osteoporosis can occur in both sexes in all age groups, but often need
menopause in women and occurs later in life in men. Unlike secondary >> << osteoporosis is the result of drugs lasix without prescription, other conditions or diseases. Examples include
induced osteoporosis,, and
-. occurs throughout adult life, with
old bones and a new bone. These cells continuously renew the skeleton while maintaining
its strength and density. Typically, the adult skeleton, 3 percent
cortical bone and 25 percent spongy bone rebuilt every year. How to lower hormone levels, fragments move forward >> and << explosions behind, leading to increased bone loss and decreased bone
replacement. After menopause, bone loss associated with
increase the number and activity of osteoclasts in spongy bone >>. << Known that estrone stimulates osteoblasts
(and, >> << forming muscle tissue). DHEA also plays a role in bone, DHEA flavored
in estrone. Testosterone, easily
in estradiol, no doubt also plays a role, in fact, one study found free >> << testosterone better biomarkers in postmenopausal spinal bone integrity. Estrogen is produced in the body plays an important role in maintaining the structure of the
and calcification of bones. With the fall in estrogen levels during menopause,
this important support removed, and the ability to absorb and assimilate
calcium is often reduced at this time. Osteoporosis involves a more balanced hormones. This is a complex >> << status with lifestyle, diet and environmental factors as well. The study concluded that prevention is the most important step, and
women of all ages should be encouraged to take from 1000 to 1500 mg of calcium
, extra day to participate in regular weight-bearing exercise,
to avoid drugs known to compromise bone density, institute hormone replacement therapy
during menopause in the absence of contraindications and avoid tobacco
and excessive alcohol consumption. World Health Organization has established a committee in 1994 to define osteoporosis. This committee created four diagnostic categories: normal, osteopenia, osteoporosis
and established osteoporosis. Osteoporosis affects 75 million people in the United States, Europe and Japan
, and results in more than 1. 3000000 fractures annually
United States. Because osteoporosis is usually asymptomatic until >> << fracture occurs, family physicians should determine the appropriate >> << terms and methods for the selection of those at risk. More Collections :: main clinical content Medscape, always updated. You can find >>
<< comprehensive on this site. (Registration is not required, but it's free).
Link added January 1, 2004.
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